Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2012
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
not specified
GLP compliance:
not specified
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
N-[2-amino-4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl]-4-methoxybenzamide
EC Number:
616-054-9
Cas Number:
74149-74-9
Molecular formula:
C19 H20 N4 O3
IUPAC Name:
N-[2-amino-4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl]-4-methoxybenzamide
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder
Details on test material:
brown odorless powder

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
-0.1
Temp.:
25 °C
Remarks on result:
other: temperature range 20 - 30 °C

Applicant's summary and conclusion

Conclusions:
logPow = -0.1
Executive summary:

The test product Aminopyridazinone has a partition coefficient (logPow, n-octanol/water) of -0.10.

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