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EC number: 939-338-7 | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Data waiving: Based on the ready biodegradability study the test substance is not toxic to microorganisms.
Absence of microbial toxicity can be inferred from biodegradation studies in the laboratory. The information content of ready biodegradability tests can be used to derive a NOEC. The assumption that the substance under investigation is not inhibitory to the micro-organisms when dosed in the test system is implicit in ready biodegradability testing. If a compound does not inhibit the degradation of a positive control at a certain concentration, this concentration can be used as a NOEC value.
Any Ready Biodegradability Test relying on continuous monitoring or the Manometric Respirometry test (OECD 301F) is considered more reliable for observing the effects of a chemical on the inoculum.
Based on the ready biodegradability study the test substance is not toxic to microorganisms since it does not inhibit the degradation of a positive control at 100 mg/L. Therefore, this concentration can be used as a NOEC value.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 100 mg/L
Additional information
Data waiving: Based on the ready biodegradability study the test substance is not toxic to microorganisms.
Absence of microbial toxicity can be inferred from biodegradation studies in the laboratory. The information content of ready biodegradability tests can be used to derive a NOEC. The assumption that the substance under investigation is not inhibitory to the micro-organisms when dosed in the test system is implicit in ready biodegradability testing. If a compound does not inhibit the degradation of a positive control at a certain concentration, this concentration can be used as a NOEC value.
Any Ready Biodegradability Test relying on continuous monitoring or the Manometric Respirometry test (OECD 301F) is considered more reliable for observing the effects of a chemical on the inoculum.
Based on the ready biodegradability study the test substance is not toxic to microorganisms since it does not inhibit the degradation of a positive control at 100 mg/L. Therefore, this concentration can be used as a NOEC value.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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