Registration Dossier
Registration Dossier
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Reaction mass of endo-2-methyl-exo-3-methyl-exo-2-[(endo-3-methylbicyclo[2.2.1]hept-endo-2-yl)methyl]bicyclo[2.2.1]heptane and endo-2-methyl-exo-3-methyl-exo-2-[(endo-2-methylbicyclo[2.2.1]hept-endo-3-yl)methyl]bicyclo[2.2.1]heptane and endo-2-methyl-exo-3-methyl-exo-2-[(exo-3-methylbicyclo[2.2.1]hept-exo-2-yl)methyl]bicyclo[2.2.1]heptane and endo-2-methyl-exo-3-methyl-exo-2-[(exo-2-methylbicyclo[2.2.1]hept-exo-3-yl)methyl]bicyclo[2.2.1]heptane
EC number: 939-299-6 | CAS number: -
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Please refer to attached justification for read across.
- Reason / purpose for cross-reference:
- read-across source
- Preliminary study:
- None reported - test conducted on a suspension of test substance at the maximum test concentration 100 mg/L
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 28 d
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 0 - 1
- Sampling time:
- 28 d
- Details on results:
- Day 0 - test substance was observed to be a suspension in the test solution (water + test substance and sludge + test substance)
Day 28 - test substance was observed to be a suspension in the test solution (water + test substance)
Day 28 - test substance was observed to be a suspension in the test solution and no growth of sludge occurred - Results with reference substance:
- 95% degradation observed for aniline after Day 28
- Validity criteria fulfilled:
- yes
- Remarks:
- 54% and 81% degradation of positive control on days 7 and 14 respectively
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The test substance was not readily biodegradable under the conditions of the test.
Reference
Vessel |
Day 7 |
Day 14 |
Day 21 |
Day 28 |
Mean Deg. |
||||
BOD (mg) |
Deg. (%) |
BOD (mg) |
Deg. (%) |
BOD (mg) |
Deg. (%) |
BOD (mg) |
Deg. (%) |
||
Sludge+ aniline |
52.4 |
54 |
83.8 |
81 |
95.9 |
92 |
101.0 |
95 |
|
Water + TS |
3.8 |
- |
10.5 |
- |
12.8 |
- |
14.8 |
- |
|
Control blank |
3.6 |
0 |
7.9 |
0 |
9.0 |
0 |
10.4 |
0 |
0 |
Sludge + TS |
3.1 |
0 |
7.8 |
0 |
9.2 |
0 |
10.2 |
0 |
|
Sludge + TS |
3.7 |
0 |
8.7 |
0 |
10.3 |
0 |
11.8 |
0 |
|
Sludge + TS |
0.0 |
- |
0.0 |
- |
0.0 |
- |
0.0 |
- |
|
Description of key information
The test substance, T-12, an analogue of the registered substance T-13h, was not readily biodegradable under the conditions of the test.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
The determination of ready biodegradability was performed by Kurume Research Laboratories (1993, Report No.: S92 -2309). The ready biodegradability was determined according to OECD Method 301 C was considered to be reliable. T-12 was found not to be readily biodegradable. T-12 is an analogue of T-13h and is considered suitable for read across. A detailed justification for read across from T-12 to T-13h, considering the overall properties and composition of the two substances, is given in section 13 (Assessment reports) of this dossier, . T-12 is a mixture of 6 diastereoisomer pairs (isomer B, C, D, E, F) and T-13h is a mixture comprising two of the diastereoiosmer pairs (D, F).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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