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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Read-across from acute oral, dermal and inhalation studies with cyanuric acid. Experimental data showed no evidence of acute toxicity to cyanuric acid.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
7 554.42 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
Value:
7 930 mg/m³

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
7 554.42 mg/kg bw

Additional information

Read-across:
1. Based on the experimental results obtained with the analogue cyanuric acid (LD50 > 5000 mg/kg bw) the read-across approach is applied and the LC50 for substance trisodium cyanurate is calculated to be higher than 7554.42 mg/kg bw (oral acute toxicity).
2. Based on the experimental results obtained with the analogue cyanuric acid (LC50 > 5.25 mg/L) the read-across approach is applied and the LC50 for substance trisodium cyanurate is calculated to be higher than 7.93 mg/L (inhalation acute toxicity).
3. Based on the experimental results obtained with the analogue cyanuric acid (LD50 > 5000 mg/kg bw) the read-across approach is applied and the LC50 for substance trisodium cyanurate is calculated to be higher than 7554.42 mg/kg bw (dermal acute toxicity).

Justification for classification or non-classification

The LD50 values exceeded the limit of classification in the oral, dermal and inhalation studies and therefore CYA need not be classified.