Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From July 17 to 27, 2001
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
Eucarol AGE SS (D-Glucopyranose, oligomeric, 6-(hydrogen 2-sulfobutanedioate), 1- (coco alkyl) ethers, sodium salts) was old name for EUCAROL AGE SS/ND before REACH regulatory - new nomenclature. The substance was identified with: CAS: 151911-53-4 EC: 500-331-5

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2011
Report Date:
2001

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
yes
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Substance type: no longer polymer
- Physical state: viscous liquid, 55.5 % in water solution
- Lot/batch No.: 2001030007
- Expiration date of the lot/batch: 01/03/2003

Results and discussion

Partition coefficientopen allclose all
Type:
Pow
Partition coefficient:
< 0.002
Temp.:
20 °C
Remarks on result:
other: pH not reported
Type:
log Pow
Partition coefficient:
-2.8
Temp.:
20 °C
Remarks on result:
other: pH not reported
Details on results:
D-Glucopyranose, oligomeric, 6-(hydrogen 2-sulfobutanedioate), 1- (coco alkyl) ethers, sodium salts is a complex mixture of different homologous, the chromatograms presented different peaks related to the test material, for the quantitative analyses a main component of the mixture was selected (peak at retention time = 2.05 minutes).
The height of the peak was measured in each chromatogram using the chromatographic software of the data station.

Applicant's summary and conclusion

Conclusions:
The n-octanol/water partition coefficient was determined at 20°C according to OECD 107.
D-Glucopyranose, oligomeric, 6-(hydrogen 2-sulfobutanedioate), 1- (coco alkyl) ethers, sodium salts has been found to be highly hydrophilic, since the analyte concentration in the n-octanol phases of the partition experiments were founded to be lower than the estimated limit of detection for the analytical method (50 ppm). In this case, the evaluation of the partition coefficient has been done considering the analytical limit of detection as the concentration limit for the n-octanol phase.

Partition coefficient value at 20°C : < 1.5 x 10^-3 (-2.8 as its decimal cologarithm).
This was the lowest value founded for all the series of partitioning tests.