Registration Dossier
Registration Dossier
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EC number: 202-751-1 | CAS number: 99-34-3
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation
- Remarks:
- in vivo
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Authoritative data base
- Title:
- Danish QSAR study for CAS No.: 99-34-3
- Author:
- Danish EPA Model
- Year:
- 2 012
- Bibliographic source:
- QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:-Commercial
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Modelling Database
- Principles of method if other than guideline:
- Multicase model A33 used for estimation of the result
- GLP compliance:
- no
- Type of study:
- not specified
Test material
- Reference substance name:
- 3,5-dinitrobenzoic acid
- EC Number:
- 202-751-1
- EC Name:
- 3,5-dinitrobenzoic acid
- Cas Number:
- 99-34-3
- Molecular formula:
- C7H4N2O6
- IUPAC Name:
- 3,5-dinitrobenzoic acid
Constituent 1
In vivo test system
Test animals
- Species:
- other: no data
- Strain:
- not specified
- Sex:
- not specified
Study design: in vivo (non-LLNA)
Induction
- Route:
- other: no data
- Vehicle:
- no data
Challenge
- Route:
- other: no data
- Vehicle:
- no data
Study design: in vivo (LLNA)
- Vehicle:
- not specified
Results and discussion
In vivo (non-LLNA)
Results
- Reading:
- 1st reading
- Group:
- test chemical
- Clinical observations:
- Skin sensitization : Positive
- Remarks on result:
- other: Reading: 1st reading. Group: test group. Clinical observations: Skin sensitization : Positive .
In vivo (LLNA)
Results
- Parameter:
- other: disintegrations per minute (DPM)
- Remarks on result:
- other: no data
Any other information on results incl. tables
Skin sensitization : Positive
Applicant's summary and conclusion
- Interpretation of results:
- sensitising
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Skin sensitization : Positive
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
