Registration Dossier
Registration Dossier
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EC number: 234-666-0 | CAS number: 12021-95-3
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxicity of the structural analogue dipotassium hexafluorozirconate to Danio rerio (zebra fish) was tested according to OECD 203; an LC50 of 125.8 mg/L was recalculated for dihydrogen hexafluorozirconate.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 125.8 mg/L
Additional information
Dihydrogen hexafluorozirconate
The acute toxicity of the structural analogue dipotassium hexafluorozirconate to Danio rerio (zebra fish) was tested according to OECD 203. An LC50 of 125.8 mg/L was recalculated for dihydrogen hexafluorozirconate indicating a similar potential for acute toxicity to fish (or a lack thereof) as other fluoride substances (see below).
Potassium fluoride
LC50 values of 107.5, 92.4, 118.5, 105.1, 64.1 ppm at 96, 120, 144, 168 and 192 h respectively are reported for rainbow trout (Camargo & Tarazona, 1991). The same authors report LC50 value for brown trout of 164.5, 135.6, 118.5, 105.1 and 97.5 ppm after 96, 120, 144, 168 and 192 h respectively. The EU RAR for hydrogen fluoride reports additional LC50 values of 299 mg/L (48h in Leuciscus idus); 51 mg/L in (96h in Onchorynchus mykiss) and 340 mg/L (96h in Gasterosteus aculeatus). The RIVM Integrated Criteria Document reports additional data, with LC50 values ranging from 128 -460 mg/L (Sloof et al, 1988). The RIVM document also reports LC50 values of >100 mg/L (the limit of solubility) for sodium fluoride in seawater.
The key value for the risk assessment is considered to be an LC50 of 51 mg/L in Onchoryhnchus mykiss reported by Janssen (1989) in the appendix to the ICD report.
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