Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study according to EU/OECD guideline.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2-Difluoroethanamine
EC Number:
671-709-6
Cas Number:
430-67-1
Molecular formula:
C2H5F2N
IUPAC Name:
2,2-Difluoroethanamine

Results and discussion

Water solubilityopen allclose all
Water solubility:
276 g/L
Temp.:
20 °C
pH:
9.95
Remarks on result:
other: experiment 1
Water solubility:
278 g/L
Temp.:
20 °C
pH:
9.91
Remarks on result:
other: experiment 2
Water solubility:
> 270 g/L
Temp.:
20 °C
pH:
9.9
Remarks on result:
other: mean resulting from 2 experiments

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): very soluble (> 10000 mg/L)
The solubility of the test item is > 270 g/L at 20°C and ph 9.9.

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