Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin irritation / corrosion
Remarks:
in vitro
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study according to OECD / EU guideline.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method B.40 (In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test (TER))
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2-difluoroethan-1-amine
EC Number:
671-709-6
Cas Number:
430-67-1
Molecular formula:
C2H5F2N
IUPAC Name:
2,2-difluoroethan-1-amine

Test system

Duration of treatment / exposure:
4h

Results and discussion

In vivo

Results
Irritation parameter:
other: optical density (OD)
Basis:
mean
Time point:
other: 4h
Score:
0
Max. score:
0
Remarks on result:
other: In this in vitro EPISKIN model test, the results indicate that the test item is not classified as a skin corrosive.
Irritant / corrosive response data:
In this in vitro EPISKIN model test with the test item, the results indicate that the test item is not classified as a skin corrosive.

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
In this in vitro EPISKIN model test with the test item, the results indicate that the test item is not classified as a skin corrosive.