Registration Dossier

Administrative data

Key value for chemical safety assessment

Effects on fertility

Effect on fertility: via oral route
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
NOAEL
1 000 mg/kg bw/day
Study duration:
subchronic
Species:
rat
Quality of whole database:
good
Effect on fertility: via inhalation route
Endpoint conclusion:
no study available
Effect on fertility: via dermal route
Endpoint conclusion:
no study available
Additional information
Short description of key information:
the developmental toxicity screening test showed no effects on reproduction at a dose level of 1000 mg/kg/bw

Effects on developmental toxicity

Description of key information
the developmental toxicity screening test showed no adverse effects on the offspring aat a maternal dose of 1000 mg/kg bw /d
Effect on developmental toxicity: via oral route
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
NOAEL
1 000 mg/kg bw/day
Study duration:
subacute
Species:
rat
Quality of whole database:
good
Effect on developmental toxicity: via inhalation route
Endpoint conclusion:
no study available
Effect on developmental toxicity: via dermal route
Endpoint conclusion:
no study available

Justification for classification or non-classification

substance need not be classified for reproductive or developmental toxicty since no adverse effects on fertility or on the development could be found in a developmental screening test at 1000 mg/kg bw /d