Registration Dossier

Administrative data

Key value for chemical safety assessment

Additional information

Justification for selection of genetic toxicity endpoint
No endpoint selected for classification: none of the availabe studies shows a positive effect

Short description of key information:
Negative in Ames test up to 5000 microgram/plate (EC B.14)
Negative in in vitro chromosome aberration test (EU B.10, OECD 473)
Negative in an in-vivo mouse bone marrow micronucleus test

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

Not classified:

Negative in Ames test up to 5000 microgram/plate (EC B.14)

Negative in in vitro chromosome aberration test (EU B.10, OECD 473)

Negative in an in-vivo mouse bone marrow micronucleus test