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EC number: 294-436-0 | CAS number: 91722-33-7 A complex combination of organic compounds separated after condensation of the vapors from the destructive distillation of wood.
The NOAEL was established on the basis of reduced weight gain in femal rats during a subchronic repeadted dose study. No observation of any specific mode of action was made.
This repeated dose 90-day oral study in rats of the sub-chronic toxicity of Scansmoke R909 fo llowing dietary administration was conducted according to GLP and to OECD guidelines, and is thus acceptable to cover this end-point.
A moderate body weight depression was observed in female rats at all dose levels. However, taking into account the lack of a clear dose response relationship and the lack of alterations in the males, the body weight depression was considered by the laboratory to be of toxicological relevance at the 20000 ppm level.
The no observed effect level (NOEL) was 20000 ppm in male rats and lower than 5000 ppm in the females. It corresponds to 1253 mg/kg bw/day in male rats and 498 mg/kg bw/day in female rats. The no observed adverse effect level (NOAEL) was 20000 ppm in male rats and 12000 ppm in female rats, corresponding to 1253 mg/kg bw/day and 1129 mg/kg bw/day, respectively.
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