Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 248-256-4 | CAS number: 27138-01-8
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The results of the study showed that under valid static test conditions, the maximum concentration causing no mortality and the 96 h-LC50 of the test item to zebra fish are both greater than the nominal concentration of 150mg/L (measured concentration 147 mg/L).
Key value for chemical safety assessment
Additional information
The acute toxicity of test item (meta-Diisopropanolbenzene) to zebra fish (Brachydanio rerio) under static conditions, was assessed according to “The guidelines for the testing of chemicals”, SEPA(HJ/T 153-2004); and with reference to Procedure 203 of the “Guidelines for Testing of Chemicals” of the OECD: "Fish, Acute Toxicity Test” (1992).
A limit test was performed with 100 mg/L and 150 mg/L. Water samples taken from the control and the test treatments in the limit test were analysed. The mean analyzed concentrations were 93.9 mg/L and 147 mg/L respectively. The analytical results showed that the concentration of the test item is consistent in the test medium throughout the 96-hour test period (deviation within 20%).
During the whole test period, all fish in the control groups and treated groups were alive and appeared normal. The results showed that under valid static test conditions, the maximum concentration causing no mortality and the 96 h-LC50of the test item to zebra fish are both greater than the nominal concentration of 150mg/L (measured concentration 147 mg/L).
The study met the acceptability criteria prescribed by the protocol (pH: 6.0~8.5; dissolved oxygen concentration: > 60% of the air saturation value; total hardness:10~250 mg(CaCO3)/L; temperature: 23±2°C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
