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Classification & Labelling & PBT assessment

PBT assessment

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PBT assessment: overall result

PBT status:
the substance is not PBT / vPvB
Justification:

Due to titanium diboride being practically insoluble in water (see section 4.8) and not containing intrinsically lipophilic functional groups, which would facilitate uptake across biological surfaces (e.g. the fish gill or digestive tract epithelium), uptake of titanium diboride across biological membranes can be excluded. Furthermore, there is no indication for the presence of specific active transport systems which would be able to transport titanium diboride through biological membranes into the blood stream or adipose tissue. Titanium diboride does not cross biological membranes and therefore cannot bioaccumulate. A risk for biomagnification, which might lead to adverse effects along the food chain, is not given. Therefore titanium diboride can be regarded as being not PBT/vPvB