Registration Dossier
Registration Dossier
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EC number: 200-929-3 | CAS number: 76-05-1
pH
Administrative data
- Endpoint:
- pH
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Non-GLP, non-guideline study, limitations in design and/or reporting but otherwise adequate for assessment.
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
- Principles of method if other than guideline:
- pH-metry
potentiometry for acid reserve
Test material
- Reference substance name:
- Trifluoroacetic acid
- EC Number:
- 200-929-3
- EC Name:
- Trifluoroacetic acid
- Cas Number:
- 76-05-1
- Molecular formula:
- C2HF3O2
- IUPAC Name:
- trifluoroacetic acid
- Test material form:
- liquid
- Details on test material:
- - Name of test material (as cited in study report): TFA
- Lot/batch No.: SFA1006230
Constituent 1
Results and discussion
pH value
- pH value:
- 0.45
- Concentration:
- 10 other: %m/m
- Remarks on result:
- other: aqueous solution
Any other information on results incl. tables
Acid reserve = 35.0 g NaOH / 100 g sample
Applicant's summary and conclusion
- Conclusions:
- TFA is of high acidity.
The information is relevant for corrosivity assessment and waiving of acute toxicity tests on animals. - Executive summary:
The acidity of Trifluoroacetic acid (TFA) was estimated by pH and acid reserve measurements. No experimental data were provided. Results are respectively 0.45 for a 10% aqueous solution, and 35g NaOH/100g.
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