Registration Dossier
Registration Dossier
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EC number: 468-670-0 | CAS number: -
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Directive 92/69/EEC, C.1 OECD 203 (1992) ISO 7346-1 (1996) Guidance document on aquatic toxicity testing of difficult substances and mixtures, OECD series on testing and assessment number 23, December 14, 2000.
- GLP compliance:
- yes
Test solutions
- Details on test solutions:
- Identity and concentration of auxiliary solvent for dispersal: A solubility pre-test in test medium confirmed that the test
substance could not be dissolved completely at 100 mg/l.
Treatment with ultrasonic waves and magnetic stirring for a
total of 15 minutes resulted in a hazy dispersion with a
thin film on the surface. A subsequent 24-hour stirring
period did not improve the dissolution.
As in addition stability in test medium was unknown, maximum
solubility was achieved by a 10-minute stirring period of a
supersaturated 100 mg/l dispersion followed by ultrasonic
treatment (11-13 minutes) and subsequent filtration through
a 0.45 µm filter (Schleicher and Schuell, RC55). The lower
test concentrations for the range-finding test were prepared
by subsequent dilution of the filtrate in test medium. The
final test solutions were all clear and colourless.
Part of the test solutions was used for the simultaneously
performed acute Daphnia magna toxicity test.
Test organisms
- Test organisms (species):
- other: Carp (Cyprinus carpio, Teleostei, Cyprinidae)
Study design
- Test type:
- semi-static
Test conditions
- Hardness:
- 250 mg CaCO3/L
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 6.9 mg/L
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- > 6.9 mg/L
- Details on results:
- %Concentration loss over test: ... 2
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
