Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 231-526-0 | CAS number: 7616-94-6
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Epidemiological data.
Data source
Reference
- Reference Type:
- publication
- Title:
- Sullivan, J.B. Jr., G.R. Krieger (eds.). Hazardous Materials Toxicology-Clinical Principles of Environmental Health. Baltimore, MD: Williams and Wilkins, 1992., p. 1196
- Year:
- 1 992
- Bibliographic source:
- Hazardous Substances Data Bank (HSDB)
Materials and methods
- Principles of method if other than guideline:
- Nethod not available
- GLP compliance:
- no
Test material
- Reference substance name:
- Perchloryl fluoride
- EC Number:
- 231-526-0
- EC Name:
- Perchloryl fluoride
- Cas Number:
- 7616-94-6
- Molecular formula:
- ClFO3
- IUPAC Name:
- perchloroyl fluoride
Constituent 1
Results and discussion
In vivo
Results
- Irritation parameter:
- other: corrosive potential
- Remarks on result:
- probability of severe irritation
Applicant's summary and conclusion
- Interpretation of results:
- Category 1 (corrosive) based on GHS criteria
- Conclusions:
- Perchloryl fluoride is a strong irritant of the eyes, mucous membranes, and lungs. In high concentration it can produce pulmonary edema as well as methemoglobinemia. Exposure to toxic concentration can produce weakness, syncope, and headache as well as severe respiratory tract irritation and pulmonary edema. Skin contact from the liquid form can produce burns.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
