hexasodium 5-[(4-{3-[(8-benzamido-1-hydroxy-3,6-disulfonato-2-naphthyl)diazenyl]-4-sulfonatoanilino}-6-[(2-sulfonatoethyl)amino]-1,3,5-triazin-2-yl)amino]isophthalate

Water solubility

Administrative data

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

The study was conducted between 18 July 2007 and 29 August 2007.

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2007

Report date:

2007

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Test material

Test material information

Constituent 1

Reference substance name:

Magenta T-43

IUPAC Name:

Magenta T-43

Test material form:

solid: particulate/powder

Details on test material:

Sponsor's identification: MAGENTA T-43
Description: dark red solid
Storage conditions: room temperature, in the dark
Lot number: H186-5

Results and discussion

Water solubility

Water solubility:

>= 30 - <= 31.9 other: % w/w

Temp.:

20 °C

pH:

7.5

Remarks on result:

other: Results reported in % w/w are equivalent to a very soluble (>10000 mg/L) interpretation of results.

Details on results:

Preliminary Test Results:
The solubility was in the range 29.9 to 39.8% w/w of solution at 20.0 ± 0.5°C.

Definitive Test:
The solubility was in the range 30.0 to 31.9% w/w of solution at 20.0 ± 0.5°C.

Any other information on results incl. tables

Results

Preliminary test results

 

The preliminary sample concentration, observations and solution pH, on completion of the 20°C equilibration period, are shown below.

 

Sample Number	Concentration (%w/w)	Observations	Solution pH
1	10.0	Red solution containing no excess test material.	7.2
2	19.9	Red solution containing no excess test material.	7.2
3	29.9	Red solution containing no excess test material.	7.5
4	39.8	Red viscous solution containing excess test material.	7.4
5	49.9	Red solid containing excess test material.	-
6	59.8	Red solid containing excess test material.	-

 

Result: solubility in the range 29.9 to 39.8% w/w of solution at 20.0 ± 0.5 °C.

Definitive Test:

 

The definitive sample concentration, observations and solution pH, on completion of the 20°C equilibration period are tabulated below.

 

Sample Number	Concentration (%w/w)	Observations	Solution pH
1	25.9	Red solution containing no excess test material.	7.3
2	28.0	Red solution containing no excess test material.	7.4
3	30.0	Red solution containing no excess test material.	7.4
4	31.9	Red solution on surface of a red gel containing excess test material	7.5
5	33.9	Red solution on surface of a red gel containing excess test material	7.5
6	36.1	Red solution on surface of a red gel containing excess test material	7.4

 

Result: solubility in the range 30.0 to 31.9% w/w of solution at 20.0± 0.5°C.

 

Applicant's summary and conclusion

Conclusions:

Interpretation of results: very soluble (> 10000 mg/L)
The water solubility of the test material was determined to be very soluble (>10000 mg/L) in the range 30.0 to 31.9% w/w of solution at 20.0 ± 0.5 °C by visual assessment.

Executive summary:

The water solubility of substance Magenta T-43 was very soluble (>10000 mg/L) with 30.0 to 31.9% w/w solubility range at 20.0 ± 0.5 °C by visual assessment according to the OECD Test Guideline 105 using the flask method.