Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 210-379-6 | CAS number: 614-33-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Glycerol tribenzoate has an extremely low practical water/media solubility (3.3 ug/L in algal test medium and 1.71 ug/L in M4 media, estimated in the analytical method).
Exhaustive attempts were made to validate an analytical method to support the aquatic ecotoxicology studies but without success. The confidential analytical report is attached for full disclosure and reference.
Pre-tests were undertaken for both the aquatic invertebrates and algal study to assist will the biology study but also to enable the analytical method to be tested.
Analytical results of these pre-tests demonstrate that the method was not suitable to determine such low levels of achieved concentration. It should be noted that dilution of the samples was not validated and used extrapolation outside of the validated calibration line and so these results are not relied upon.
In so supporting the analytical method development, the number of replicates / organisms to meet the requirements of a limit test was achieved for both the algae and daphnia test and these results are presented here.
In conclusion, Glycerol tribenzoate is not toxic to algae and daphnia when dose at a rate of up to 100 mg/L.
Additional information
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