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EC number: 950-968-1 | CAS number: -
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- The study was conducted according to an internationally recognised method, but without detailed documentation, and with technical inaccuracy (distant extrapolation). The test substance is adequately identified. Therefore validation applies with restrictions.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 23rd March 2006
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- Regulation (EC) No 440/2008
- GLP compliance:
- no
- Type of method:
- dynamic method
- Temp.:
- 25 °C
- Vapour pressure:
- 0.001 mBar
- Temp.:
- 25 °C
- Vapour pressure:
- 0.1 Pa
- Conclusions:
- Low volatility (based on volatility bands criteria for occupational exposure (Chesar / ECETOC TRA),
<< 500 Pa). - Executive summary:
The vapour pressure of the test substance was measured according to OECD104 guideline, dynamic (ebulliometer) method.
Eight measurements were recorded between 157 and 210°C. The coefficients of the non-linear Riedel's and Antoine's equations between VP and 1/T were calculated.
From this relationship, the extrapolated vapour pressure of the substance is 0.1 Pa at 25°C- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- The study was conducted according to an internationally recognised method, but without detailed documentation, and with technical inaccuracy (distant extrapolation). The test substance is adequately characterised. Therefore validation applies with restrictions.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 23rd March 2006
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- Regulation (EC) No 440/2008
- GLP compliance:
- no
- Type of method:
- dynamic method
- Temp.:
- 25 °C
- Vapour pressure:
- 0.001 mBar
- Temp.:
- 25 °C
- Vapour pressure:
- 0.1 Pa
- Conclusions:
- Low volatility (based on volatility bands criteria for occupational exposure (Chesar / ECETOC TRA), << 500 Pa).
- Executive summary:
The vapour pressure of the test substance was measured according to OECD104 guideline, dynamic (ebulliometer) method.
Eight measurements were recorded between 156 and 213°C. The coefficients of the non-linear Antoine's equation between VP and 1/T were calculated.
From this relationship, the extrapolated vapour pressure of the substance is 0.1 Pa at 25°C.
Referenceopen allclose all
Temperature [°C] | Pressure [mbar] |
157 | 10.9 |
170 | 18.7 |
| 179 | 27.4 |
| 180 | 28.4 |
| 183 | 31.7 |
| 197 | 53.8 |
| 209 | 83.5 |
| 210 | 86.5 |
Antoine's equation:
P(T) = (1013.25/760)*10E{A - [B/(T+C)]} (mbar)
Parameters (for 0 - 100 mbar):
A= 7.46, B= 2287.73, C= 191.48
Riedel's equation:
P(T) = (EXP(A-B/Tr+C*ln(Tr)+D*((Tr)^6)))*Pc
Parameters:
A= 14.4465, B= 14.4570, C= -5.9199, D= 0.00001
Tc* = 475.88°C
Tr = (T+273.15)/(Tc+273.15)
Pc*= 18435.07 mbar
Pr = P/Pc
Temperature [°C] | Pressure [mbar] |
156 | 10.1 |
165 | 14.8 |
| 168 | 16.9 |
| 181 | 28.3 |
| 190 | 40.0 |
| 198 | 53.4 |
| 204 | 67.2 |
| 213 | 90.1 |
Antoine's equation:
P(T) = 10E{A - [B/(T+C)]}*(1013.25/760) (mbar)
Parameters:
A= 8.03, B= 2658.08, C= 215.48
Description of key information
Low volatility.
Key value for chemical safety assessment
- Vapour pressure:
- 0.1 Pa
- at the temperature of:
- 25 °C
Additional information
A reliable experimental study, conducted according to a recognized OECD method, is available. Despite restrictions on accuracy due to extrapolation, it is considered as a key study, and the extrapolated result at 25°C is retained as key value.
This value is consistent with the supporting experimental result on the analogue and major constituent.
It should be noted that, due to the multi-isomers nature of the substance, this result may refer to the most volatile one.
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