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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
Qualifier:
according to
Guideline:
EU Method C.2 (Acute Toxicity for Daphnia)
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes
Analytical monitoring:
yes
Test organisms (species):
Daphnia magna
Details on test organisms:
TEST ORGANISM
- Common name: Daphnia magna (Straus)
- Strain/clone: clone 5
- Age at study initiation (mean and range, SD): < 24 hours old
- Source: LIEBE - CNRS UMR 7146 - UFR SciFA - Université de Lorraine Campus Bridoux - Bât. IBISE, 8, rue du Général Delestraint - 57070 METZ, bred in the Laboratoires des Pyrénées et des Landes.

Test type:
static
Water media type:
other: reconstituted water
Limit test:
no
Total exposure duration:
48 h
Remarks on exposure duration:
None
Post exposure observation period:
No
Details on test conditions:
TEST SYSTEM
- Test vessel: glass tubes
- Type (delete if not applicable): loosely capped test tubes
- Material, size, headspace, fill volume: 15 mL capacity glass tubes, filled with 9.95 mL of reconstituted water
- No. of organisms per vessel: 5 daphnids / unit
- No. of vessels per concentration (replicates): four replicate unites for each five treatment concentrations
- No. of vessels per control (replicates): 4 replicates for the water control and 4 replicates for the solvent control.
- Reference item treatment : Potassium dichromate was tested at three different concentrations and with four replicates per concentration.

Reference substance (positive control):
yes
Key result
Duration:
48 h
Dose descriptor:
EC50
Conc. based on:
test mat.
Basis for effect:
mobility
Remarks on result:
other: On-going
Conclusions:
The EC50 (48h) for the immobilization of Daphnia magna by the test substance (On-going)
Executive summary:

The influence of the test substance on immobilisation of Daphnia magna was investigated according to OECD Guideline 202, with GLP statement. Daphnids were exposed to the test item under static conditions, for 48 h. The results are not yet available (Study on going).

Description of key information

Study on-going.

Key value for chemical safety assessment

Additional information

The influence of the test substance on immobilisation of Daphnia magna was investigated according to OECD Guideline 202, with GLP statement. Daphnids were exposed to the test item under static conditions, for 48 h. The results are not yet available (Study on going).