4,4'-(4-methylpentane-2,2-diyl)bis((heptyloxy)benzene)

Water solubility

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

07 January 2019 - 08 March 2019

Reliability:

1 (reliable without restriction)

Qualifier:

equivalent or similar to guideline

Guideline:

EU Method A.6 (Water Solubility)

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Qualifier:

equivalent or similar to guideline

Guideline:

EPA OPPTS 830.7840 (Water Solubility)

GLP compliance:

yes

Type of method:

flask method

Specific details on test material used for the study:

Identification: 4,4'-(4-methylpentane-2,2-diyl)bis((heptyloxy)benzene)
Batch (Lot) Number: AS455433
Expiry date: 01 November 2020 (retest date) (taken from label)
Physical Description: Colourless to light yellow viscous liquid
Purity/Composition: 98.5%
Storage Conditions: At room temperature protected from light

Key result

Water solubility:

ca. 0.023 mg/L

Conc. based on:

test mat. (dissolved fraction)

Temp.:

20 °C

pH:

>= 7 - <= 7.2

Conclusions:

The slow-stirring flask method was applied for the determination of the water solubility and the ISO-medium solubility of 4,4'-(4-methylpentane-2,2-diyl)bis((heptyloxy)benzene).
The water solubility of the test item at 20°C was < 0.023 mg/L. The pH of the aqueous samples was between 7.0 – 7.2.

Executive summary:

Two methods are available for the determination of the water solubility of a liquid test item. Both methods are based on the flask method in which the mass concentration of the test item in aqueous solutions saturated with the test item is determined after stirring or shaking at a specific temperature for a specific period of time.

Flask method

For test items with a water solubility of ≥ 10^-2 g/L the vessels will be shaken or stirred at a speed of > 100 rpm.

Slow-stirring Flask Method

For test items with a water solubility of<10^-2g/L additional care must be taken to avoid intensive mixing of the test item with the water phase and slow-stirring at a stirring speed of≤ 100 rpm will be applied.

A preliminary test was carried out as a range-finding test prior to performance of the main study.

The slow-stirring flask method was applied for the determination of the water solubility and the ISO-medium solubility of 4,4'-(4-methylpentane-2,2-diyl)bis((heptyloxy)benzene).

The water solubility of the test item at 20°C was < 0.023 mg/L. The pH of the aqueous samples was between 7.0 – 7.2.

Reference 2

Endpoint:

water solubility

Remarks:

the ISO-medium solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

07 January 2019 - 08 March 2019

Reliability:

1 (reliable without restriction)

Qualifier:

equivalent or similar to guideline

Guideline:

EU Method A.6 (Water Solubility)

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Qualifier:

equivalent or similar to guideline

Guideline:

EPA OPPTS 830.7840 (Water Solubility)

GLP compliance:

yes

Type of method:

flask method

Specific details on test material used for the study:

Identification: 4,4'-(4-methylpentane-2,2-diyl)bis((heptyloxy)benzene)
Batch (Lot) Number: AS455433
Expiry date: 01 November 2020 (retest date) (taken from label)
Physical Description: Colourless to light yellow viscous liquid
Purity/Composition: 98.5%
Storage Conditions: At room temperature protected from light

Key result

Water solubility:

0.051 mg/L

Conc. based on:

test mat. (dissolved fraction)

Temp.:

20 °C

pH:

>= 6.8 - <= 7.1

Remarks on result:

other: ISO-medium solubility

Conclusions:

The slow-stirring flask method was applied for the determination of the water solubility and the ISO-medium solubility of 4,4'-(4-methylpentane-2,2-diyl)bis((heptyloxy)benzene).
The solubility of the test item in ISO-medium at 20°C was < 0.051 mg/L. The pH of the aqueous samples was between 6.8 - 7.1.

Executive summary:

Two methods are available for the determination of the water solubility of a liquid test item. Both methods are based on the flask method in which the mass concentration of the test item in aqueous solutions saturated with the test item is determined after stirring or shaking at a specific temperature for a specific period of time.

Flask method

For test items with a water solubility of ≥ 10^-2 g/L the vessels will be shaken or stirred at a speed of > 100 rpm.

Slow-stirring Flask Method

For test items with a water solubility of<10^-2g/L additional care must be taken to avoid intensive mixing of the test item with the water phase and slow-stirring at a stirring speed of≤ 100 rpm will be applied.

A preliminary test was carried out as a range-finding test prior to performance of the main study.

The slow-stirring flask method was applied for the determination of the water solubility and the ISO-medium solubility of 4,4'-(4-methylpentane-2,2-diyl)bis((heptyloxy)benzene).

The solubility of the test item in ISO-medium at 20°C was < 0.051 mg/L. The pH of the aqueous samples was between 6.8 - 7.1.

Description of key information

The slow-stirring flask method was applied for the determination of the water solubility and the ISO-medium solubility of 4,4'-(4-methylpentane-2,2-diyl)bis((heptyloxy)benzene).

The water solubility of the test item at 20°C was < 0.023 mg/L.  The pH of the aqueous samples was between 7.0 – 7.2.

The solubility of the test item in ISO-medium at 20°C was < 0.051 mg/L.  The pH of the aqueous samples was between 6.8 - 7.1.

Key value for chemical safety assessment

Water solubility:

0.023 mg/L

at the temperature of:

20 °C