Glutamic acid

Bioaccumulation: aquatic / sediment

Administrative data

Endpoint:

bioaccumulation in aquatic species: fish

Type of information:

other: SIDS

Adequacy of study:

other information

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Data source

Reference

Reference 1

Reference Type:

publication

Title:

SIDS for L-Glutamic acid

Author:

OECD

Year:

2013

Report date:

2013

Reference 2

Reference Type:

other: QSAR-tool

Title:

Estimations Programs Interface (EPI) Suite™ for Microsoft Windows®, v4.10

Author:

US EPA (U.S. Environmental Protection Agency)

Year:

2011

Materials and methods

Test material

Specific details on test material used for the study:

Test material equivalent to submission substance identity:
yes

Test conditions

Details on test conditions:

Details on estimation of bioconcentration
[BASIS FOR CALCULATION OF BCF]
- Estimation software: BCFBAF ver.3.01
- Summary Results:
Log BCF (regression-based estimate): 0.50 (BCF=3.16 L/kg wet-wt)
Biotransformation Half-Life (days): 0.00946 (normalized to 10 g fish)
Log BAF (Arnot-Gobas upper trophic): -0.05 (BAF=0.893 L/kg wet-wt)
Log Kow (experimental): -3.69
Log Kow used by BCF estimates: -3.69
Equation Used to Make BCF estimate: Log BCF = 0.50 (Ionic; Log Kow dependent)
Estimated Log BCF = 0.500 (BCF = 3.162 L/kg wet-wt)

Results and discussion

Bioaccumulation factor

Key result

Type:

BCF

Value:

3.162 dimensionless

Applicant's summary and conclusion

Conclusions:

Using log Kow of -3.69, a BCF of 3.162 was calculated with BCFBAF, version 3.01. This chemical is not expected to bioaccumulate.