5-diethoxymethyl-1,3-benzodioxole

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2019

Report date:

2019

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

effusion method: Knudsen cell

Test material

Test material information

Constituent 1

Reference substance name:

5-diethoxymethyl-1,3-benzodioxole

EC Number:

254-956-0

EC Name:

5-diethoxymethyl-1,3-benzodioxole

Cas Number:

40527-42-2

Molecular formula:

C12H16O4

IUPAC Name:

5-(diethoxymethyl)-2H-1,3-benzodioxole

impurity 1

Reference substance name:

Piperonal

EC Number:

204-409-7

EC Name:

Piperonal

Cas Number:

120-57-0

Molecular formula:

C8H6O3

IUPAC Name:

1,3-benzodioxole-5-carbaldehyde

Specific details on test material used for the study:

Batch no.: 18030042
Appearance: colorless to pale yellow liquid
Purity: 99% (GC)
Homogeneity: homogeneous
Production date: 14. Mar. 2018
Expiry date: 14. Mar. 2019
Storage: Room Temperature (20 ± 5°C) store under inert gas in the dark

Results and discussion

Vapour pressure

Vapour pressure 1

Key result

Temp.:

ca. 20 °C

Vapour pressure:

ca. 0.243 Pa

Vapour pressure 2

Key result

Temp.:

ca. 25 °C

Vapour pressure:

ca. 0.401 Pa

Vapour pressure 3

Key result

Temp.:

ca. 30 °C

Vapour pressure:

ca. 0.688 Pa

Vapour pressure 4

Key result

Temp.:

ca. 45 °C

Vapour pressure:

ca. 2.25 Pa

Vapour pressure 5

Key result

Temp.:

ca. 60 °C

Vapour pressure:

ca. 9.17 Pa

Any other information on results incl. tables

The vapour pressure of the test item was determined at four different temperatures (30, 45, 60 and 75 °C) according to OECD 104 resp. EU A.4 using the effusion method (weight loss). Experiment 4 (nominal temperature 75°C) showed no reproducible weight loss. When visible contaminations, caused by explosive evaporation of the test item, were observed, the cells were meticulously cleaned and weighed. This weight was used as initial weight for the subsequent measurements. To avoid bias, these measurements were not used forcalculations.

Three experiments could be evaluated as they showed relevant and reproducible weight loss. All evaluated experiments showed good repeatability, giving relative standard deviations of less than 27% (limit value from the guideline 30%) and good correlation.

Therefore, the result of the test can be considered valid.

Applicant's summary and conclusion

Conclusions:

According to OECD 104 test guideline, the vapour pressures of the test item is 2.43E-01 Pa at 20°C and 4.01E-01 Pa at 25°C.