(2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol

Surface tension

Link to relevant study record(s)

Reference

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From July 29 to September 6, 2005

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

The study was conducted according to an internationally recognised method, and under GLP. No deviation affected the quality of the study. The substance is considered to be adequately characterised with its purity. Therefore full validation applies.

Reason / purpose for cross-reference:

reference to other study

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Deviations:

no

Principles of method if other than guideline:

Not applicable

GLP compliance:

yes (incl. QA statement)

Remarks:

UK GLP Compliance Programme (inspected on April 12, 2005/ signed on June 01, 2005)

Type of method:

OECD harmonised ring method

Key result

Surface tension:

46.5 mN/m

Temp.:

20 °C

Conc.:

548 mg/L

Remarks on result:

other:

Remarks:

The concentration of 548 mg/L results from 90% of the water solubility (609 mg/L)

Calibration

Literature value for the surface tension of water at 20°C = 72.7 mN/m.

Measured surface tension of water at 20°C = 72.0 mN/m.

Calibration factor = 1.010

Table 4.10/1: Surface tension – results

 

Time (minutes)	Surface tension (mN/m)
	Measured		Calibration corrected
	A	B	A	B
0	50.0	50.0	50.5	50.5
5	49.0	50.0	49.5	50.5
10	49.0	49.5	49.5	50.0
15	49.0	49.0	49.5	49.5
20	49.0	49.0	49.5	49.5
25	49.0	49.0	49.5	49.5
30	49.0	49.0	49.5	49.5

 

From the results there was slight time dependence of surface tension after transfer to the measuring vessel. The mean of the values from 15 to 30 minutes was determined.

Overall mean calibration corrected surface tension = 49.5 mN/m

Harkins-Jordan corrected value = 46.5 mN/m

Conclusions:

According to EU A5 criteria, as the result is below the threshold value of 60 mN/m, the substance is considered to have surface-active potential under the experimental conditions.

Executive summary:

The surface tension of the test substance was measured under GLP according to OECD 115/EU A5 guidelines, OECD harmonised ring method.

Two replicates were performed, at 90 % of the saturation solubility, and the mean of the consistent values was corrected with calibration factor from water.

 

The surface tension of the test solution was found to be 46.5 mN/m (at 20°C).

Description of key information

Experimental surface tension on a ca 90% saturated solution.

According to EU A5 criteria, as the result is below the threshold value of 60 mN/m, the substance is considered to have surface-active potential under the experimental conditions. However, since the structure is not characteristic of a true surfactant, and it is not the intended use of the substance (i.e. not a desired property), this conclusion should be taken with caution.

Key value for chemical safety assessment

Surface tension:

46.5

in mN/m at 20°C and concentration in mg/L:

548

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. Therefore, it is considered as a key study, and the result is retained as key value.

As the surface tension result is less than 60 mN/m, the tested material is considered to be surface active.