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Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
October 25 - November 07, 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
The study was conducted according to an internationally recognised method, and under GLP. The test substance is adequately characterised. Therefore full validation applies.
Qualifier:
according to
Guideline:
OECD Guideline 103 (Boiling Point)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.2 (Boiling Temperature)
Version / remarks:
2008
Deviations:
no
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes (incl. certificate)
Remarks:
GLP compliance programme (inspected on 20-21 June 2017 / signed on 4 September 2017)
Type of method:
differential scanning calorimetry
Key result
Boiling pt.:
>= 160 - <= 385 °C
Atm. press.:
101.3 kPa

Results

Boiling point / boiling range:DSC measurement

Two DSC measurements in aluminium crucibles with a hole were performed. The crucibles were cooled to -50 °C and -80°C, respectively, with a rate of 1 K/min and hold at this temperature for 5 h. Afterwards followed heating with a rate of 10 K/min. Two endothermal effects followed in the temperature range of 160 – 385 °C. No further endothermal or exothermic effects were observed up to the final temperature (500 °C). The mass loss after the DSC measurements amounted to 100 %.

The onset temperature was derived from the intersection of the tangent line with the highest slope of the endothermal peak with the baseline.

The results of the DSC measurements are summarized in table below.

Table 4.3.1.-Boiling point (DSC measurement)

Ident No.

Test item /

mg

Starting temperature

/ °C

Final test temperature

/ °C

Temperature range (endo-thermal)

/ °C

Onset 

(boiling)

/ °C

Crucible

Observations after the measurement

38309

12.37

-50

500

160 – 280

300 – 370

209.6

321.9

Aluminium with a hole

The crucible was empty

38312

12.01

-80

500

190 – 270

310 – 385

210.6

324.6

Aluminium with a hole

The crucible was empty

Due to the broad endothermal signals for boiling the 2ndmeasurement was not evaluated here (see figures on the experimental report).

Graphical presentations of the DSC runs are shown on the experimental report

According to the certificate of analysis the test item is UVCB substance. Thus from the results of the DSC measurements a boiling range is stated. The test item showed a multistage boiling in the temperature range of 160 – 385 °C.

Conclusions:
The boiling point of the substance was determined under experimental circumstances within the following range: (160-385 °C) using DSC method.
Executive summary:

The boiling point of the test item was measured under GLP according to OECD 103 / EU A2 guideline, by DSC.

3 runs were performed.

Two endothermal effects followed in the temperature range of 160 – 385 °C. No further endothermal or exothermic effects were observed up to the final temperature (500 °C). The mass loss after the DSC measurements amounted to 100 %. The test item showed a multistage boiling in the temperature range of 160 – 385 °C. These values are the results of two independent measurements using DSC method.

Note that these results may vary with the substance composition and should therefore be considered with caution. No observations were made which might cause doubts on the validity of the study outcome. Therefore, the result of the study is considered valid.

Description of key information

The boiling range of the substance was determined under experimental circumstances within the following range: (160 - 385 °C) using DSC method.

Key value for chemical safety assessment

Additional information

A reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. It is considered as a key study. The result being expressed as a range, it cannot be retained as (single) key data.