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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
January 25, 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
Study conducted according to internationally accepted testing guidelines. Although the values recorded are outside of the applicability domain for the test method, the rusults can be considered as reliable and representative for the tested substance. The study outcomes are indicative of a high affinity with the water phase, respect than the octanol one.
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
no
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water
Analytical method:
photometric method
Type:
Pow
Partition coefficient:
0.013
Temp.:
20 °C
pH:
6.68
Type:
log Pow
Partition coefficient:
-1.894
Temp.:
20 °C
pH:
6.68
Conclusions:
log Pow: -1.8941 at 20 °C and at pH of 6.68
Executive summary:

Partition coefficient was determined by means of shake flask method as per recommendations of OECD 107. Partition coefficient (P) is defined as the ratio of the equilibrium concentrations of a dissolved substance in a two-phase system consisting in two largely immiscible solvents.

Study conducted at 20 °C and at pH of 6.68.

Average Pow: 0.0129

Average log Pow: -1.8941

Conclusion

log Pow: -1.8941 at 20 °C and at pH of 6.68

Description of key information

Average log Pow: -1.8941, at 20 °C and pH 6.68

Key value for chemical safety assessment

Log Kow (Log Pow):
-1.894
at the temperature of:
20 °C

Additional information

Shake flask method - OECD 107