Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 236-860-0 | CAS number: 13518-93-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance has a low octanol water partition coefficient and the adsorption potential of this substance is related to this parameter
- Endpoint:
- adsorption / desorption
- Remarks:
- adsorption
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 2009
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Two QSAR estimations are performed. One is described in the EU Technical Guidance Document, the other is used by the UDS EPA.
- Principles of method if other than guideline:
- QSAR estimation by 2 methods.
- GLP compliance:
- no
- Type of method:
- other: QSAR
- Radiolabelling:
- no
- Test temperature:
- Not relevant.
- Analytical monitoring:
- not required
- Details on sampling:
- Not relevant.
- Details on matrix:
- Not relevant.
- Details on test conditions:
- Not relevant.
- Computational methods:
- Adsorption coefficient per organic carbon (Koc):
1) Using the equation provided in the ECB Technical Guidance Document of 2000 for triazines: logKoc = 0.30 logKow + 1.5 and logKow = -1.22.
Result: logKoc = 1.13.
2) Using the programme KOCWIN v2.00:
Result based on molecular connectivity index: logKoc = 1.51.
(Result based on a calculated logKow of -1.37: logKoc = 0.0002.) - Type:
- log Koc
- Value:
- 1.13
- Conclusions:
- Melamine has an estimated low ability to adsorb to soil.
- Executive summary:
Adsorption coefficient per organic carbon (Koc):
1) Using the equation provided in the ECB Technical Guidance Document of 2000 for triazines: logKoc = 0.30 logKow + 1.5 and logKow = -1.22
Result: logKoc = 1.13.
2) Using the programme KOCWIN v2.00:
Result: logKoc = 1.51.
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Justification for type of information:
- Please refer to the analogue justification attached to section 13
- Reason / purpose for cross-reference:
- read-across source
- Type:
- log Koc
- Value:
- 1.13 dimensionless
- Remarks on result:
- other: Source, Supporting, RA-A, CAS 108-78-1, QSAR.
Referenceopen allclose all
Adsorption coefficient per organic carbon (Koc):
1) Using the equation provided in the ECB Technical Guidance Document of 2000 for triazines:
logKoc = 0.30 logKow + 1.5 and logKow = -1.22: -> logKoc = 1.13.
2) Using the programme KOCWIN v2.00:
Based on molecular connectivity index: logKoc = 1.51.
(Based on a calculated logKow of -1.37: logKoc = 0.0002.)
Description of key information
Key value for chemical safety assessment
Additional information
Experimental data on the transport of diphosphoric acid, compound with 1,3,5-triamine (1:2) are not available. Based on the experimentally determined low log Pow of the substance (log Pow -1.24 at 20 °C, OECD 107) a low adsorption potential of the substance is expected.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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