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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 2018-02-07 to 2018-02-13
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
static method
Specific details on test material used for the study:
- Batch No.of test material: 20141015
- Purity: 99.35%
- Expiration date of the lot/batch: January 2019
- Stability under test conditions: Room temperature
Key result
Temp.:
20 °C
Vapour pressure:
8.5 Pa
Remarks on result:
other: mean of runs 1 & 2

Full test results:

Temp / °C

Temp / K

P / mbar

P / Pa

Run 1

*20

293.15

0.09

9

20.6

293.75

0.0911

9.11

29.8

302.95

0.172

17.2

39.9

313.05

0.2887

28.87

50.0

323.15

0.5398

53.98

Run 2

*20

293.15

0.08

8

20.9

294.05

0.081

8.1

30.5

303.65

0.166

16.6

40.1

313.25

0.2687

26.87

50.0

323.15

0.4655

46.55

* Determined by extrapolation

Run 1: 10.8 g of sample was degassed for a 70 hour period. Starting vacuum pressure was 0.0063 mbar.

Run 2: 12.5 g of sample was degassed for a 94 hour period. Starting vacuum pressure was 0.0029 mbar.

Conclusions:
The vapor pressure of the test item has been determined to be 8.5 Pa at 20 ºC.

Description of key information

A GLP-compliant study was performed to determine the vapour pressure according to EU Method A.4 without deviations (K1, Dekra, 2018). A vapour pressure of 8.5 Pa was determined at 20°C using the vapour pressure balance method.

Key value for chemical safety assessment

Vapour pressure:
8.5 Pa
at the temperature of:
20 °C

Additional information