Registration Dossier
Registration Dossier
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EC number: 205-181-1 | CAS number: 135-16-0
Surface tension
Administrative data
Link to relevant study record(s)
- Endpoint:
- surface tension
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018-01-05 to 2018-02-16
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 115 (Surface Tension of Aqueous Solutions)
- Version / remarks:
- 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.5 (Surface Tension)
- Version / remarks:
- 2008
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- OECD harmonised ring method
- Key result
- Surface tension:
- 64.75 mN/m
- Temp.:
- 20.1 °C
- Conc.:
- 1 g/L
- Conclusions:
- The surface tension of a 1 g/L (saturated) aqueous solution of the test item Tetrahydrofolic acid was determined to be 64.75 mN/m (standard deviation e 0.05 mN/m) at 20 °C, Considering that distilled water has a surface tension of 72.75 mN/m at 20 °C and the test item showed a surface tension above 60 mN/m under the conditions of this referring method, the test item should be regarded as being not surface-active material.
Reference
Table 1: Surface Tension; Temperature
Measurement No 1) |
Time 2) [min] |
Time 3) [min] |
Surface Tension [mN/m] |
Temperature |
1 |
103.25 |
55.72 |
64.67 |
20.1 |
2 |
104.00 |
56.47 |
64.69 |
20.1 |
3 |
104.76 |
57.22 |
64.71 |
20.1 |
4 |
105.51 |
57.97 |
64.75 |
20.1 |
5 |
106.26 |
58.72 |
64.75 |
20.1 |
6 |
107.01 |
59.47 |
64.75 |
20.1 |
7 |
107.76 |
60.23 |
64.76 |
20.1 |
8 |
108.51 |
60.97 |
64.82 |
20.1 |
9 |
109.25 |
61.72 |
64.81 |
20.1 |
10 |
110.oo |
62.47 |
64.80 |
20.1 |
Mean |
|
|
64.75 |
20.1 |
SD [±] |
|
|
0.05 |
0.0 |
SD = standard deviation
1 ) of the last 10 measurements
2) Time from preparation of test solution in the test vessel until end of each measurement
3) Time from start of measurement until end of each measurement
Description of key information
Surface tension: 64.75 mN/m at 20°C (OECD 115, GLP)
Key value for chemical safety assessment
- Surface tension:
- 64.75
- in mN/m at 20°C and concentration in mg/L:
- 1 000
Additional information
The surface tension of a 1 g/L (saturated) aqueous solution of the test item Tetrahydrofolic acid was determined to be 64.75 mN/m (standard deviation e 0.05 mN/m) at 20 °C, Considering that distilled water has a surface tension of 72.75 mN/m at 20 °C and the test item showed a surface tension above 60 mN/m under the conditions of this referring method, the test item should be regarded as being not surface-active material.
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