Registration Dossier

Administrative data

Description of key information

The acute oral toxicity of Ketimine resin was examined in rats. The test substance was given undiluted by gavage, in one single dose of 10.0 mL per kg body weight to 5 male and 5 female rats. After treatment none of th rats showed any sign of intoxication. No deaths occured and all rats looked quite healthy throughout the observation period. The oral LD50 of ketimine resin was found to exceed 10.0 mL per kg body weight (equivalent to 9400 mg/kg, considering a relative density of 0.94 g/cm3).

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
LD50
Value:
9 400 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Justification for classification or non-classification

The oral LD50 of ketimine resin was found to exceed 10.0 mL per kg body weight (equivalent to 9400 mg/kg, considering a relative density of 0.94 g/cm3), hence the GHS criteria are not met.