Poly(oxy-1,2-ethanediyl), alpha-[2-[bis(2-aminoethyl)methylammonion)ethyl]-, omega-hydroxy, N,N'-di-Limnanthes alba seed oil acyl derivatives, methyl sulfates (salts)

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

10th July 2018 - 8th August 2018

Reliability:

1 (reliable without restriction)

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Version / remarks:

27 July 1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Version / remarks:

Commission Regulation (EC) No 440/2008 of 30 May 2008

Deviations:

no

GLP compliance:

yes

Other quality assurance:

ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)

Type of method:

flask method

Specific details on test material used for the study:

Identification: RM1004942
Appearance/Physical State: Amber colored paste
Batch Number: RL149/17
Expiry date: 08 September 2018

Key result

Water solubility:

< 0.001 g/L

Conc. based on:

test mat.

Incubation duration:

35 min

Temp.:

20 °C

pH:

>= 5.92 - <= 6.23

Remarks on result:

other: The substance may not have reached full saturation equilibrium in the visual assessment and that degradation products may have influenced the result.

Preliminary test results.

Preliminary number	Observation
1	Opaque pale yellow suspension
2	Slightly hazy solution
3	Slightly hazy solution

Definitive Visual Assessment

Sample	Observation
Unfiltered	Slightly hazy solution that gave a faint Tyndall beam effect
Filtered	Very slightly hazy solution that gave a faint Tyndall beam effect

Conclusions:

The water solubility of the substance was evaluated by visual inspection and determined to be less than 9.7 x 10-4 g/L.

Executive summary:

Water solubility test has been conducted in accordance with OECD TG 105 using a flask method. Based on the preliminary results, a low level mixture of substance and purified water was prepared in order to determine a limit value following 35 min of shaking and ultra-sonication. During preliminary water solubility tests it was discovered that excess substance could not be removed from saturated test solutions. A combination of filtration (as low as 0.1μm) and centrifugation (at speeds up to 13000 rpm) could not remove the excess substance. Therefore, the water solubility was estimated by visual inspection. It should be noted that the substance may not have reached full saturation equilibrium in the visual assessment and that degradation products may have influenced the result. The water solubility of the substance has been determined to be less than 9.7 x 10-4 g/L.

Description of key information

The water solubility of the substance was evaluated by visual inspection and determined to be less than 9.7 x 10-4 g/L.

Key value for chemical safety assessment

Water solubility:

0.001 g/L

at the temperature of:

30 °C

Additional information

It should be noted that the substance may not have reached full saturation equilibrium in the visual assessment and that degradation products may have influenced the result.