Registration Dossier
Registration Dossier
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EC number: 302-766-4 | CAS number: 94134-01-7
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro cytogenicity / chromosome aberration study in mammalian cells
- Type of information:
- other: expert assessment
- Adequacy of study:
- weight of evidence
- Study period:
- 2018
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: An assessment was performed based on available data on the individual constituents of the substance
Data source
Reference
- Reference Type:
- other: expert assessment
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- An assessment was performed based on available data on the individual constituents of the substance
- GLP compliance:
- no
- Type of assay:
- in vitro mammalian chromosome aberration test
Test material
- Reference substance name:
- N,N-bis(carboxymethyl)glycine, compound with 2-aminoethanol (1:3)
- EC Number:
- 302-766-4
- EC Name:
- N,N-bis(carboxymethyl)glycine, compound with 2-aminoethanol (1:3)
- Cas Number:
- 94134-01-7
- Molecular formula:
- C6H9NO6.3C2H7NO
- IUPAC Name:
- 2-[bis(carboxymethyl)amino]acetic acid; tris(2-aminoethan-1-ol)
- Test material form:
- solid: bulk
Constituent 1
Results and discussion
- Remarks on result:
- other: N,N’-bis(carboxymethylglycine) compound with 2-aminoethanol (1:3) is not expected to induce structural chromosomal aberration in mammalian cells.
Applicant's summary and conclusion
- Conclusions:
- N,N’-bis(carboxymethylglycine) compound with 2-aminoethanol (1:3) is not expected to induce structural chromosomal aberration in mammalian cells.
- Executive summary:
An assessment was performed based on available data on the individual constituents of the substance. It was concluded that N,N’-bis(carboxymethylglycine) compound with 2-aminoethanol (1:3) is not expected to induce structural chromosomal aberration in mammalian cells.
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