Registration Dossier
Registration Dossier
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EC number: 302-766-4 | CAS number: 94134-01-7
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- April 17, 2001 to May 18, 2001
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- < 0
- Temp.:
- 20.9 °C
- pH:
- 10.4
- Details on results:
- One (1) peak on the elution profile for monoethanolamine salt of nitrilotriacetic acid was registered with log Pow value <0. The test item was completely soluble in methanol:water 3:1 and gave a clear solution at a concentration of 1.0 mg/ml.
- Conclusions:
- One (1) peak on the elution profile for monoethanolamine salt of nitrilotriacetic acid was registered with log Pow value <0. The n-octanol-water partition coefficient was concluded to be log Pow <0.
- Executive summary:
A study compliant with GLP and in line with OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method) was performed to determine the n-octanol-water partition coefficient of monoethanolamine salt of nitrilotriacetic acid. One (1) peak on the elution profile was registered with log Pow value <0. It can be concluded that monoethanolamine salt of nitrilotriacetic acid has an n-octanol-water partition coefficient of log Pow <0.
Reference
Description of key information
A n-octanol-water partition coefficient of log Pow <0 was obtained for monoethanolamine salt of nitrilotriacetic acid in line with OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method).
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 0
- at the temperature of:
- 20.9 °C
Additional information
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