Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient - Shake Flask Method)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Reference substance name:
Zanthoxylum, ext.
EC Number:
310-094-8
EC Name:
Zanthoxylum, ext.
Cas Number:
102242-62-6
Molecular formula:
NA
IUPAC Name:
Zanthoxylum, ext.
Test material form:
liquid: viscous

Study design

Analytical method:
gas chromatography

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
20.2
Temp.:
22 °C
pH:
ca. 7

Any other information on results incl. tables

The partition coefficient (P) is defined as the ratio of the equilibrium concentrations of a dissolved substance in a two-phase system consisting of two largely immiscible solvents. Being the quotient of two concentrations, it is dimensionless and is usually given in the form of its logarithm to base ten (Log10P). Since the test item “Zanthoxylum Extract” is an UCVB substance in sense of REACH classification, more peaks are present in the GC chromatogram. One peak is taken as representative of the mix. Therefore an accurate value cannot be given. An inferior range is presented.

Results of Partition coefficient:

No peak was observed in water solvent. Therefore the lowest level of recovery (LOQ) was taken as minimum amount observable in water

Applicant's summary and conclusion

Conclusions:
No peak was observed in water solvent. Therefore the lowest level of recovery (LOQ) was taken as minimum amount observable in water