Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
column elution method

Test material

Constituent 1
Reference substance name:
Zanthoxylum, ext.
EC Number:
310-094-8
EC Name:
Zanthoxylum, ext.
Cas Number:
102242-62-6
Molecular formula:
NA
IUPAC Name:
Zanthoxylum, ext.
Test material form:
liquid: viscous

Results and discussion

Water solubility
Key result
Water solubility:
0.022 g/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
ca. 7

Any other information on results incl. tables

   Medium   Temp (°C)   Flow rate (mL/h)   Solubility (g/L)

  Mean +- SD (g/L)

   Pure water

 20

 12.5

 0.0208 - 0.0201 - 0.0193 - 0.0218 - 0.0189

 0.0202 +-0.00117

 Medium

 Temp (°C)

 Flow rate (mL/h)

 Solubility (g/L)

 Mean +- SD (g/L)

 Pure water 20  25   0.01178 - 0.0206 - 0.0229 - 0.0239 - 0.0230  0.0217 +-0.00247

Applicant's summary and conclusion

Conclusions:
The means calculated on the two tests at the different flows, have a repeatability of less than 7 %, then the solubility is 0.02095 g/L.