Registration Dossier
Registration Dossier
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EC number: 619-301-9 | CAS number: 97928-20-6
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Data source
Materials and methods
- GLP compliance:
- not specified
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: feed
- Vehicle:
- methylcellulose
- Details on oral exposure:
- No toxic symptons were observed. LD0 > 4000 mg/kg. Acute toxicity of LAS W-090 by oral administration in rat and mouse is almost negligible, since the animals tolerate 4000 mg/kg without any mortality being observed (which for physical reasons prevents determination of DL50). The results of the study in the dog support the apparent low toxicity of LAS-090 after oral administration.
- Doses:
- 4000 mg/kg
Results and discussion
Effect levels
- Key result
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 4 000 mg/kg bw
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- Not toxic.
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