Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Remarks:
Not mutagenic
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail

Data source

Materials and methods

GLP compliance:
not specified

Method

Species / strainopen allclose all
Species / strain / cell type:
S. typhimurium TA 1535, TA 1537, TA 98 and TA 100
Species / strain / cell type:
S. typhimurium TA 1538
Metabolic activation:
with and without

Results and discussion

Test resultsopen allclose all
Key result
Species / strain:
S. typhimurium TA 1535
Metabolic activation:
with and without
Genotoxicity:
other: no evidence
Species / strain:
S. typhimurium TA 1537
Metabolic activation:
with and without
Genotoxicity:
other: no evidence
Species / strain:
S. typhimurium TA 1538
Metabolic activation:
with and without
Genotoxicity:
other: no evidence
Species / strain:
S. typhimurium TA 98
Metabolic activation:
with and without
Genotoxicity:
other: no evidence
Species / strain:
S. typhimurium TA 100
Metabolic activation:
with and without
Genotoxicity:
other: no evidence

Applicant's summary and conclusion