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EC number: 214-014-1
CAS number: 1072-71-5
tested for acute toxicity towards daphnia according to OECD-Test
Guideline 202 (version dated 13-Apr-2004) in compliance with GLP. In
order to investigate the influence of the test item towards the daphnia,
the swimming behaviour of the animals was recorded. Under the conditions
used for the test, there was an immobilisation of the daphnia at
concentrations >2 mg/L. As a conclusion
of the analytical part of this study, it can be stated that the
sufficiently stable during incubation of 48hr. As
a result of the supporting analysis it can be stated that the results of
the biological part should be based on the nominal concentrations
applied because the recoveries of the nominal concentrations were all
following EC-values (effective concentrations) were determined
Basis: Nominal Concentrations [mg/L]
= not determined for mathematical reasons.
test is considered valid as all conditions for validity were met.
Short-term toxicity to aquatic
invertebrates: NOEC (24h) ≥ 10 mg/L and NOEC (48h) = 2.00 mg/L, EC50(
24h) > 10 mg/L and EC50 (48h) = 5.95 mg/L for Daphnia magna (OECD 202,
There is a Klimisch 1 OECD 202 (Daphnia
magna over 48h) study available, indicating that the test item does
not need to be classified as acute toxic to the aquatic environment.
With regard to chronic toxicity, the test item should be classified as
aquatic chronic Cat. 2 according to Regulation (EC) No 1272/2008 and
amendments, taking into account the facts that the test item is soluble
in water, i.e. above the determined EC50 value, and not readily
In this study, the results were NOEC (48h) =
2.00 mg/L and EC50 (48h) = 5.95 mg/L. There is no indication given that
this data is not relevant for the assessment of ecotoxicological
properties of DMTD. Hence, no data gap was identified, and the key value
of EC50 = 5.95 mg/L, can be chosen for further risk assessment.
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