Registration Dossier
Registration Dossier
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EC number: 228-193-9 | CAS number: 6163-58-2
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 09 October 2017 to 08 November 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
- Specific details on test material used for the study:
- Lot number: 2000850599
- Key result
- Water solubility:
- 0.022 mg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 6.9
- Remarks on result:
- other:
- Remarks:
- Mean of the concentrations obtained at both flow rates
- Details on results:
- The results for the samples taken at a flow rate of 12 and 24 mL/h are given in Table 6.
The coefficient of variation (CV) (n = 10) was ≤ 30% at both flow rates. It demonstrated that the system was equilibrated at all flow rates.
The maximum difference (MD) on the mean values of the samples at both flow rates was also ≤ 30%. Based on this, the water solubility of the test item is given as the mean value of these measurements.
The turbidity of the eluates at 24 mL/hour was < 0.2 NTU. According to this, no undissolved particles were detected in the eluates. However, the turbidity of the eluates at 12 mL/hour was 0.214 NTU. Since the deviation from the criterion was minor there is no impact on the results.
No test item was detected in the samples from the blank column. - Conclusions:
- The column elution method was applied for the determination of the water solubility of
Tri-o-tolylphosphine.
The water solubility of the test item at 20°C was 0.022 mg/L.
The pH of the aqueous samples was 6.9.
Reference
Description of key information
The water solubility of the test item at 20°C was 0.022 mg/L.
The pH of the aqueous samples was 6.9.
Key value for chemical safety assessment
- Water solubility:
- 0.022 mg/L
- at the temperature of:
- 20 °C
Additional information
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