Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Manufacture, use & exposure

Uses at industrial sites

Uses at industrial sites

Registration/ Notification status for the use:
use registered according to REACH Article 10; total tonnage manufactured/imported <10tonnes/year per registrant
Use name:
Tri-o-tolyphosphine is used on site as a reagent in a pharmaceutical drug
Reference
Name:
Tri-o-Tolyphosphine
Type of composition:
legal entity composition of the substance
State / form:
solid: bulk
Reference substance:
Tri-o-Tolyphosphine
Contributing activity / technique for the environment
Name of activity / technique:
used on site as a reagent in a pharmaceutical drug process
Environmental release category (ERC):
ERC4: Use of non-reactive processing aid at industrial site (no inclusion into or onto article)
Contributing activity / technique for workersopen allclose all
Name of activity / technique:
Use in the synthesis of another substance in a closed reactor.
Process category (PROC):
PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
Name of activity / technique:
Charging of the substance in a contained reactor
Process category (PROC):
PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
Name of activity / technique:
Subdivision may be required but is completed in a downflow booth if required
Process category (PROC):
PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
Name of activity / technique:
Sampling and laboratory analysis
Process category (PROC):
PROC 15: Use as laboratory reagent
Product category used:
PC 29: Pharmaceuticals
Sector of end use:
SU 9: Manufacture of fine chemicals
Substance supplied to that use in form of:
as such
Subsequent service life relevant for this use:
no
Insignificant exposure via the following route:
oral
dermal
eye
inhalatory
Insignificant release via the following route:
water
air
soil
waste
Pattern of exposure:
accidental / infrequent