Registration Dossier

Administrative data

Description of key information

Acute skin irritation to the rabbit
Acute Eye irritation to the rabbit

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

Acute irritation studies were performed on the skin and eye of rabbits.

Skin irritation/corrosion: No skin irritation was caused after 4 hours exposure to E-AF098T (Fyrolflex SOL-DP) in any of the tested animals.

Eye irritation: Conjunctival redness and/or chemosis were seen in two rabbits at 1 -hour scoring interval and persisted in one rabbit at the 24 -hour interval. A small corneal opacity was seen in one of the rabbits at the 24 -hour scoring interval. All rabbits were completely recovered from all signs of ocular irritation by the 48 -hour scoring interval.

Justification for classification or non-classification

The above results triggered no classification under the EEC criteria for classification and labelling requirements for Dangerous Substances and Preparations (67/548/EEC) and the CLP Regulation (EC No 1272/2008). Therefore, Fyrolflex SOL-DP does not have to be classified and has no obligatory labelling requirement for skin irritation or eye irritation.