Glycine hydrochloride

Flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the experience in production or handling shows that the substance does not react with water, e.g. the substance is manufactured with water or washed with water

Reference 2

Endpoint:

flammable gases

Data waiving:

study technically not feasible

Justification for data waiving:

the study does not need to be conducted because the substance is a solid

Reference 3

Endpoint:

pyrophoric liquids

Data waiving:

study technically not feasible

Justification for data waiving:

the study does not need to be conducted because the substance is a solid

Reference 4

Endpoint:

pyrophoric solids

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is known to be stable in contact with air at room temperature for prolonged periods of time (days) and hence, the classification procedure does not need to be applied

Reference 5

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.1 (Test method for readily combustible solids)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.10 (Flammability (Solids))

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Key result

Test procedure:

burning rate test: preliminary screening test

Remarks on result:

substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period

Safety Pre-Test

A small amount of the test item was heated on a magnesia groove with a gas burner in order to derive safety precautions. The test item melted into a brown liquid. The liquid carbonized und black residue was observed.

Preliminary Screening Test

In the preliminary screening test following the EU and UN method, the test item was heated with the flame of a teclu burner for two minutes. The test item melted into a black-brown liquid. No signs of ignition were observed.

Interpretation of results:

GHS criteria not met

Conclusions:

The test item was considered as not highly flammable (for EU regulations) and as non-flammable solid (for UN regulations).

Executive summary:

A preliminary screening test was performed in accordance with UN Method N.1 and Commission Regulation (EC) No. 440/2008 method A.10. in order to determine the flammability of the test item by using a teclo burner. The test item was heated with the flame of the teclu burner for 2 minutes. During this time the test item melted into a black-brown liquid and no signs of ignition or flammability were observed. Hence, the test item was considered as not highly flammable according to EU regulations and as non-flammable solid according to UN regulations.

Description of key information

The substance has not to be classified as flammable gas, flammable liquid, flammable solid, pyrophoric solid, pyrophoric liquid, flammable in contact with water, flammable aerosol or self-heating substance.

Key value for chemical safety assessment

Flammability:

not classified

Additional information

Flammable solids (reference 4.13-1)

A preliminary screening test was performed in accordance with UN Method N.1 and Commission Regulation (EC) No. 440/2008 method A.10. in order to determine the flammability of the test item by using a teclo burner. The test item was heated with the flame of the teclu burner for 2 minutes. During this time the test item melted into a black-brown liquid and no signs of ignition or flammability were observed. Hence, the test item was considered as not highly flammable according to EU regulations and as non-flammable solid according to UN regulations.

Flammable gases (reference 4.13-2)

The test item is a solid at ambient conditions. This hazard class is only applicable for gases. Thus, the substance was not considered for classification as flammable gas.

Flammable liquid (reference 4.11-1)

The test item is a solid at ambient conditions. This hazard class is only applicable for liquids. Thus, the substance was not considered for classification as flammable liquid.

Pyrophoric solids (reference 4.13-3)

In accordance with Regulation (EC) No. 1272/2008, Annex I, section 2.9.4 and ECHA guidance on the application of CLP Criteria, section 2.10.4.2 the classification procedure for pyrophoric solids need not be applied when experience in manufacturing or handling shows that the substance or mixture does not ignite spontaneously when coming into contact with air at normal temperatures. Based on the experience in handling and use the substance is not known to ignite spontaneously when coming into contact with air at normal temperatures. Thus, no study was conducted and the substance was not considered for classification as pyrophoric solid.

Pyrophoric liquids (reference 4.13-4)

The test item is a solid at ambient conditions. This hazard class is only applicable for liquids. Thus, the substance was not considered for classification as pyrophoric liquid.

Substances which, in contact with water, emit flammable gases (reference 4.13-5)

In accordance with column 2 of REACH Annex VI and with Regulation (EC) No 1272/2008 Annex I section 2.12.4.1(b) the classification procedure for this hazard class need not to be applied. Based on the experience in handling and use the substance does not react with water and in addition the test substance is not pyrophoric. Thus, no study was conducted and the substance was not considered for classification.

Self-heating substances and mixtures (reference 4.13-6)

In accordance with column 2 of REACH Annex VII and ECHA guidance on IR/CSA chapter R7a, the self-heating study does not need to be performed if preliminary results exclude self-heating of the substance up to 400°C.. The test item was determined to be not self-igniting up to the melting range of 173 - 177 °C under the test conditions of EU A.16. Thus, the test UN N.4 for self-heating substances was omitted as self-heating up to the melting point can be excluded.

Flammable Aerosols

Section 2.4.2 of Guidance on the application on the CLP Criteria states as follows: “Aerosols, this means aerosol dispensers, are any non-refillable receptacles made of metal, glass or plastics and containing a gas compressed, liquefied or dissolved under pressure, with or without a liquid, paste or powder, and fitted with a release device allowing the contents to be ejected as solid or liquid particles in suspension in a gas, as a foam, paste or powder or in a liquid state or in a gaseous state." Thus, as the substance does not meet the definition for aerosol, the test for aerosols was waived. Consequently the substance has not to be considered for classification for this hazard class.

In conclusion the substance has not to be considered as flammable gas, flammable liquid, flammable solid, flammable in contact with water, flammable aerosol, pyrophoric solid, pyrophoric liquid or self-heating substance.

Justification for classification or non-classification

Classification, Labelling, and Packaging Regulation (EC) No. 1272/2008

In accordance with Annex I Section 2.2, Section 2.3, Section 2.6, Section 2.7, Section 2.9, Section 2.10, Section 2.11 and Section 2.12 of Regulation (EC) No. 1272/2008, as amended for tenth time in Regulation (EC) No. 2017/776, and UN GHS Rev 7 (2017) the test item has not to be classified as, flammable liquid, readily combustible solid in class 4 Division 4.1, self-heating substance in Class 4 Division 4.2, substances which in contact with water emit flammable gases in Class 4 Division 4.3, pyrophoric liquid, pyrophoric solid in class 4 Division 4.2, flammable gases in class 2 or as aerosol in class 2.