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EC number: 246-377-7 | CAS number: 24636-31-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
The substance, 3-(chlorodimethylsilyl)propyl methacrylate, is not stable in water, which affects the approach to the determination of physicochemical properties.
3-(Chlorodimethylsilyl)propyl methacrylate is a liquid at standard temperature and pressure, with a melting point of <-80°C, and a predicted boiling point of 210°C at 1013 hPa. It has a predicted density of 1.0 g/cm3 at 20°C and a predicted vapour pressure of 9.6 Pa at 25°C.
The substance is not classified for flammability according to Regulation (EC) No. 1272/2008 on the basis of a measured flash point of 112 ± 1.0°C at 1013 hPa and a predicted boiling point of 210°C at 1013 hPa. It has a measured auto-ignition temperature of 301°C at 1013 hPa, and is not explosive and not oxidising on the basis of structural examination.
In contact with water, 3-(chlorodimethylsilyl)propyl methacrylate reacts rapidly (half-life of <1 minute at pH 4, pH 7 and pH 9 and 25°C) to produce 3-[hydroxy(dimethyl)silyl]propyl methacrylate and hydrochloric acid according to the following equation:
CH2=C(CH3)C(=O)OCH2CH2CH2Si(CH3)2Cl + H2O → CH2=C(CH3)C(=O)OCH2CH2CH2Si(CH3)2OH+ HCl
Therefore, requirements for testing of water-based physicochemical properties for the substance are waived on the basis of instability in water. The properties of the silanol hydrolysis product, 3-[hydroxy(dimethyl)silyl]propyl methacrylate are assessed instead.
The silanol hydrolysis product, 3-[hydroxy(dimethyl)silyl]propyl methacrylate, may undergo condensation reactions in solution to produce the siloxane dimer and establish a dynamic equilibrium. The overall rate of condensation is dependent on nominal loading, temperature, and pH of the system, as well as what else is present in the solution.
The condensation reactions of monosilanols may be modelled as an equilibrium between monomer and dimer. The reaction is reversible unless the dimer concentration exceeds its solubility; in this case, the dimer forms a separate phase, driving the equilibrium towards the dimer. For 3-[hydroxy(dimethyl)silyl]propyl methacrylate, at loadings above about 30 mg/l the concentration of the dimer is predicted to exceed its solubility, resulting in formation of a separate phase. In addition, the dimer is expected to have a high volatility from water and this may cause losses from water under some conditions. Further information is given in a supporting report (PFA 2016am) attached in Section 13.
The saturation concentration in water of the silanol hydrolysis product, 3-[hydroxy(dimethyl)silyl]propyl methacrylate is limited by condensation reactions that can occur over time at loadings above approximately 30 mg/l. However, it has a predicted water solubility of 330 mg/l at 20°C using a validated QSAR method and has a log Kow 2.6. It is not expected to be surface active and it is much less volatile than the parent substance (vapour pressure = 4.8E-02 Pa at 25°C, predicted).
Reference:
PFA (2016am). Peter Fisk Associates, Silanols and aquatic systems, 404.105.003
Additional information
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