Registration Dossier

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.1 mg/L
Assessment factor:
1 000
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
1 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
10 µg/L
Assessment factor:
10 000
Extrapolation method:
assessment factor
PNEC marine water (intermittent releases):
0.1 mg/L

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
100 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
4 270.36 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
427.036 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
850.663 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
PNEC oral
PNEC value:
3.3 mg/kg food
Assessment factor:
300

Additional information

The calculation of the PNECs for tetrakis(2-ethylhexyl) benzene-1,2,4,5-tetracarboxylate (CAS 3126-80-5) is performed in accordance with “Guidance of Information Requirements and Chemical Safety Assessment, Chapter R.10 (2008): Characterisation of dose-response for environment”.

The PNECaqua(freshwater), PNECaqua(marine water), PNECintermittent release, PNECSTP and PNECoral were derived by application of an assessment factor.

The PNECs for sediments (freshwater and marine water) and soil are derived using the Equilibrium Partitioning Method (EPM) which is in concordance with ECHA REACH Guidance R.10 (“Guidance of Information Requirements and Chemical Safety Assessment, Chapter R.10: Characterisation of dose-response for environment”). The required normalized organic-carbon soil coefficient (Koc) value was determined by testing according to OECD Guideline 121 (Timmer, 2018). The calculation of the Henry´s Law Constant of the test material was performed by using US-EPA software EPIWIN/HENRYWIN v3.20. Furthermore, no PNEC for the atmospheric compartment (PNECair) has been calculated. It is considered as not relevant based on the chemical structure and intrinsic properties of the test item tetrakis(2-ethylhexyl) benzene-1,2,4,5-tetracarboxylate.

Conclusion on classification

Environmental classification and labelling

Valid experimental results are available for evaluating environmental fate and ecotoxicity. For the test item tetrakis(2-ethylhexyl) benzene-1,2,4,5-tetracarboxylate or its structural analogue (CAS 3319 -31 -1), short-term data referring to the toxicity to fish, aquatic invertebrates and aquatic algae is available.

The substance showed low to inherent biodegradation (Timmer, 2018) and was assessed to be not readily/rapidly biodegradable.

Acute toxicity data for three trophic levels (i.e. fish, daphnids and algae) is also available for the structural analogue (CAS 3319-31-1) of the test substance tetrakis(2-ethylhexyl) benzene-1,2,4,5-tetracarboxylate. All obtained effect levels (EL50, LL50) were found to be > 100 mg/L. In addition no toxic effects of the source substance to microorganisms were found in an OECD 209 test. The derived EC(3h)50 was > 1000 mg/l (nominal). Based upon the obtained experimental results the test item has not to be classified and labelled with respect to environmental hazards according to Regulation (EC) No 1272/2008.