Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 221-508-0 | CAS number: 3126-80-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Determination of 'Ready' Biodegradability was performed in a Carbon Dioxide (CO2) Evolution Test (Modified Sturm Test) in compliance with the OECD guideline No. 301 B (1992). In addition, the procedures were designed to meet the test methods of the ISO standard 10634, 1995. The study was conducted according to GLP.The test item was tested in duplicate at a target concentration of 16.5 mg/L, corresponding to 12 mg TOC/L. The organic carbon content was based on the molecular formula. The Theoretical CO2 production (ThCO2) of the test substance was calculated to be 2.63 mg CO2/mg.The relative biodegradation values calculated from the measurements performed during the test period revealed 13% and 0% biodegradation of test item (based on ThCO2), for the duplicate bottles tested. Thus, the criterion for ready biodegradability (at least 60% biodegradation within a 10 -day window) was not met. In conclusion, test substance was not readily biodegradable under the conditions of the modified Sturm test presently performed.
Additional information
Supporting information:
Prediction of tetrakis(2-ethylhexyl) benzene-1,2,4,5-tetracarboxylate is 'Non Readily Biodegradable' using the model Ready Biodegradability Sarpy rule set by Istituto di Ricerche Farmacologiche Mario Negri from VEGA QSAR Model.
Prediction is "biodegrades fast" using BIOWIN 1 and 2 models by EPI Suite software v4.1.
Using Biowin 3 from EPI Suite v4.1 software, the expected ultimate biodegradation timeframe is days to weeks
Using Biowin 4 from EPI Suite v4.1 software, the expected primary biodegradation timeframe is days
Using Biowin 5 from EPI Suite v4.1 software, the substance is expected to be readily biodegradable.
Using Biowin 6 from EPI Suite v4.1 software, the substance is expected to be readily biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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