Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
> 6.5
Temp.:
20 °C
Remarks on result:
other: pH not provided
Details on results:
The retention time of the 2,6-Di-tert-butyl-4-nonylphenol was > 40 min and hence longer than the retention time of the reference material with the highest logPow, i.e., a logPow of 6.5 (4,4´-DDT). Therefore the logPow of 2,6-Di-tert-butyl-4-nonylphenol is reported to be > 6.5.
Conclusions:
logPow: > 6.5
Executive summary:

In the Klimisch 1 GLP-study Bär (2016) determined the logPow of 2,6-Di-tert-butyl-4-nonylphenol according to OECD 117 (HPLC-method). The retention time of the 2,6-Di-tert-butyl-4-nonylphenol was > 40 min and hence longer than the retention time of the reference material with the highest logPow, i.e., a logPow of 6.5 (4,4´-DDT). Therefore the logPow of 2,6-Di-tert-butyl-4-nonylphenol is reported to be > 6.5.

The information is considered relevant and reliable for the risk assessment.

Description of key information

log Pow: > 6.5

Key value for chemical safety assessment

Log Kow (Log Pow):
6.5
at the temperature of:
20 °C

Additional information

In the Klimisch 1 GLP-study Bär (2016) determined the logPow of 2,6-Di-tert-butyl-4-nonylphenol according to OECD 117 (HPLC-method). The retention time of the 2,6-Di-tert-butyl-4-nonylphenol was > 40 min and hence longer than the retention time of the reference material with the highest logPow, i.e., a logPow of 6.5 (4,4´-DDT). Therefore the logPow of 2,6-Di-tert-butyl-4-nonylphenol is reported to be > 6.5.

The information is considered relevant and reliable for the risk assessment.