Butyl ethyl ether

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2017-01-20 to 2017-03-13

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

no

Type of method:

flask method

Specific details on test material used for the study:

- Purity: 98.4%
- Physical State: liquid
- Colour: colourless

Key result

Water solubility:

2.88 g/L

Conc. based on:

test mat.

Incubation duration:

29 d

Temp.:

20 °C

pH:

ca. 5

Details on results:

The mean calculated water solubility of sample no. 292/17 is 2.88 g/L at 20 °C ± 0.5 °C. The examined pH values are approx. pH 5 in all sample solutions.

Table 1: Sampling of aliquots of flask 1

Date of sampling	Test duration [d]	pH (approx.) [-]	Calculated water solubility (n = 2) [g/L](1	Deviation from the previous measurement [%]
14/02/17	6	5	2,24	-
15/02/17	7	5	2,04	-8,93
24/02/17	16	5	2,21	+8,33
03/03/17	23	5	2,01	-9,05
09/03/17	29	5	2,32	+15,4
		mean (n = 10)	2,17
		SD	0,15
		RSD [%]	6,88

(1): mean of dilution factor 5000 and 12500

Table 2: Final examination:

Flask no.	Weigh-in [g]	Volume (water) [mL]	pH (approx.)	Calculated water solubility (n=2) [g/L]^(1)
2	1.4420	75	5	2.99
3	1.4614	75	5	3.00
4	1.4307	75	5	2.64
5	-	75	5	-
			Mean (n=6)	2.88
			SD	0.19
			RSD [% ]	6.64

(1): mean of dilution factor 5000 and 12500

Conclusions:

The test item butyl ethyl ether has a water solubility of 2.88 g/L at 20 °C ± 5 °C according to OECD Guideline 105.

Executive summary:

According to the OECD Guideline 105, the test item butyl ethyl ether has a water solubility of 2.88 g/L at 20 °C ± 5 °C using flask method for determination and headspace GC-(EI)MS with external calibration for analytics. The examination was conducted in triplicate. Furthermore, pH of the sample solutions was approximately 5. The Tyndall effect was also examined and was negative at any point of sampling.

Description of key information

According to the OECD Guideline 105, the test item butyl ethyl ether has a water solubility of 2.88 g/L at 20 °C ± 5 °C using flask method for determination and headspace GC-(EI)MS with external calibration for analytics. The examination was conducted in triplicate. Furthermore, pH of the sample solutions was approximately 5. The Tyndall effect was also examined and was negative at any point of sampling.

Key value for chemical safety assessment

Water solubility:

2.88 g/L

at the temperature of:

20 °C