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Diss Factsheets
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EC number: 616-145-3 | CAS number: 74852-61-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no hazard identified
Marine water
- Hazard assessment conclusion:
- no hazard identified
STP
- Hazard assessment conclusion:
- no hazard identified
Sediment (freshwater)
- Hazard assessment conclusion:
- no hazard identified
Sediment (marine water)
- Hazard assessment conclusion:
- no hazard identified
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no hazard identified
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Three short-term studies were available for the three standard aquatic organisms (fish, daphnia and algae). All three studies showed no toxicity up to the highest concentration tested being 100 mg/L. The substance did not show toxic effects to fish, aquatic invertebrates at its saturation level in the respective test medium. PNECs could not be derived as the substance showed no toxic effects in studies performed in the range of its solubility. The substance is not expected to pose an unacceptable risk to the aquatic environment since it is not harmful to aquatic organisms up to its limit of solubility in water and there is expected to be very low aquatic exposure based on its very low solubility in water.
No toxicity was observed in a OECD 209 study at the highest dose tested. No PNEC can thus be derived.
As there are no tests on sediment and soil dwelling organisms available, and as no PNEC aquatic could be derived, no PNEC values for soil and sediment can be derived either by using assessment factors or by the equilibrium partitioning method.
As the substance is insoluble in water, concentrations which are toxic to aquatic organisms will not be reached. This is demonstrated in the available acute ecotoxicity studies. The substance will therefore not be classified for environmental hazards, based on the available information.
Conclusion on classification
Classification
T001325 is not considered to be biodegradable. Three short-term studies were available for the three standard aquatic organisms (fish, daphnia and algae). All three studies showed no toxicity up to the highest concentration tested being 100 mg/L. The substance did not show toxic effects to fish, aquatic invertebrates at its saturation level in the respective test medium. Classification should only be based on toxic responses observed in the soluble range, therefore the substance is not expected to be chronically toxic to aquatic organisms either based on the results of the algae study (NOEC >= solubility limit). Furthermore, the substance does not have a significant potential to bioaccumulate which is further evidence that the substance does not have the potential to be chronically toxic to aquatic organisms. Since the test substance showed not toxic effects within the range of solubility and is not bioaccumulative due to a log Pow of 3.4, the classification with aquatic chronic 4 according to Regulation (EC) N° 1272/2008 is not justified anymore. In conclusion, none of the criteria of Regulation (EC) N° 1272/2008 have been met.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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