Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Guidance on information requirements and chemical safety assessment Chapter R.6: QSARs and grouping of chemicals

Data source

Reference
Reference Type:
other: The Estimation Programs Interface (EPI) Suite TM
Title:
Unnamed
Year:
2017

Materials and methods

Principles of method if other than guideline:
Estimation of the short-term toxicity to aquatic invertebrates by the use of ECOSAR.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test organisms

Test organisms (species):
other: fish

Results and discussion

Effect concentrations
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
79.17 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.

Applicant's summary and conclusion

Conclusions:
For the short-term toxicity to fish a LC50 value of 79.17 mg/L could be calculated by ECOSAR. This value is in line with the information in the Annex III Inventory (ECHA list). Here it is mentioned, that the Danish QSAR database contains information indicating that the substance has a 96h LC50 to fish of 79.07 mg/L.